Receptor agonist
A molecule that binds to and activates a receptor, triggering a biological response. Semaglutide is a GLP-1 receptor agonist; ipamorelin is a ghrelin receptor agonist.
Frequently Asked Questions
What is Receptor agonist?
Why is Receptor agonist important in peptide research?
Related Terms
A molecule that binds to a receptor without activating it, blocking the natural ligand from binding. Used in research to study receptor function and as therapeutic agents.
Binding affinityThe strength of interaction between a peptide and its target receptor, typically expressed as a dissociation constant (Kd). Lower Kd values indicate stronger binding and generally higher potency.
EfficacyThe maximum therapeutic effect a peptide can produce regardless of dose. Distinct from potency — a peptide can be less potent but have greater efficacy, meaning it produces a larger maximum effect.
SelectivityThe ability of a peptide to preferentially bind to one receptor subtype over others. Ipamorelin is considered a selective GH secretagogue because it stimulates GH release without significantly affecting cortisol or prolactin.
Related Peptide Profiles
A GLP-1 receptor agonist FDA-approved for type 2 diabetes (Ozempic) and weight management (Wegovy). Reduces appetite and slows gastric emptying.
IpamorelinA selective growth hormone secretagogue that stimulates GH release through the ghrelin receptor with minimal effect on cortisol or prolactin.