Pharmacodynamics
The study of what a peptide does to the body — its mechanism of action, therapeutic effects, and side effects at the molecular, cellular, and organ level. Complements pharmacokinetics.
Frequently Asked Questions
What is Pharmacodynamics?
Why is Pharmacodynamics important in peptide research?
Related Terms
The study of how the body absorbs, distributes, metabolizes, and excretes a peptide over time (what the body does to the drug). Described by parameters including Cmax, Tmax, AUC, half-life, and clearance.
Dose-response curveA graph showing the relationship between peptide dose and the magnitude of biological effect. Typically S-shaped (sigmoidal), with a threshold dose, linear range, and plateau at maximum effect.
Receptor agonistA molecule that binds to and activates a receptor, triggering a biological response. Semaglutide is a GLP-1 receptor agonist; ipamorelin is a ghrelin receptor agonist.
EfficacyThe maximum therapeutic effect a peptide can produce regardless of dose. Distinct from potency — a peptide can be less potent but have greater efficacy, meaning it produces a larger maximum effect.