Oxidation
A chemical reaction that can damage methionine and cysteine residues in peptides, reducing activity. Oxidation is accelerated by light, heat, and oxygen exposure. Prevented by proper storage in amber vials with desiccant.
Frequently Asked Questions
What is Oxidation?
Why is Oxidation important in peptide research?
Related Terms
The breakdown of a peptide through chemical processes like oxidation, deamidation, or hydrolysis. Degredation reduces potency and may produce inactive or harmful byproducts. Proper storage conditions minimize degradation.
StabilityA peptide’s resistance to chemical degradation over time. Affected by temperature, pH, light, and oxidation. Lyophilized peptides are most stable; reconstituted peptides should be refrigerated and used within 28 days.
UV protectionShielding peptides from ultraviolet light, which accelerates oxidation and degradation. Achieved through amber vials, opaque packaging, and dark storage conditions.
Oxidative stressAn imbalance between free radical production and antioxidant defenses, causing cellular damage. Mitochondrial peptides (SS-31, MOTS-c, Humanin) and GHK-Cu reduce oxidative stress through different mechanisms.