Lyophilization
The freeze-drying process that removes water from a peptide solution by sublimation under vacuum. Creates a stable, shelf-stable powder with a characteristic "puck" or "cake" appearance in the vial.
Frequently Asked Questions
What is Lyophilization?
Why is Lyophilization important in peptide research?
Related Terms
A freeze-dried peptide in powder form. Lyophilization removes water to create a shelf-stable product that must be reconstituted with bacteriostatic water before injection.
ReconstitutionThe process of dissolving a lyophilized (freeze-dried) peptide powder with bacteriostatic water or sterile water before injection. Proper reconstitution technique is critical — the diluent should be added slowly along the vial wall to avoid damaging the peptide.
StabilityA peptide’s resistance to chemical degradation over time. Affected by temperature, pH, light, and oxidation. Lyophilized peptides are most stable; reconstituted peptides should be refrigerated and used within 28 days.
Peptide storageThe conditions required to maintain peptide stability and potency. Lyophilized peptides should be stored at -20°C for long-term or 2–8°C for short-term. Reconstituted peptides must be refrigerated and used within 28 days.