Analog
A synthetic peptide with a modified amino acid sequence compared to the natural version, designed to improve potency, stability, or half-life. Semaglutide is an analog of natural GLP-1 with 94% sequence homology.
Frequently Asked Questions
What is Analog?
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Related Terms
The specific linear order of amino acids in a peptide chain, written from N-terminus to C-terminus. The sequence determines the peptide’s three-dimensional structure and biological activity.
Half-lifeThe time required for the concentration of a peptide in the body to decrease by half. Determines dosing frequency — short half-life peptides (minutes) need daily dosing, while long half-life peptides (days) can be dosed weekly.
PotencyThe amount of a peptide required to produce a given effect. A more potent peptide achieves the same effect at a lower dose. Measured by EC50 — lower EC50 means higher potency.
Related Peptide Profiles
A GLP-1 receptor agonist FDA-approved for type 2 diabetes (Ozempic) and weight management (Wegovy). Reduces appetite and slows gastric emptying.
SermorelinA synthetic GHRH analog (first 29 amino acids of GHRH) used to stimulate natural growth hormone production. Previously FDA-approved for GH deficiency diagnosis.