Aggregation
The clumping together of peptide molecules, which can reduce biological activity and potentially cause injection-site reactions. Prevented by proper reconstitution technique (gentle swirling, not shaking) and correct storage temperature.
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Related Terms
A peptide’s resistance to chemical degradation over time. Affected by temperature, pH, light, and oxidation. Lyophilized peptides are most stable; reconstituted peptides should be refrigerated and used within 28 days.
ReconstitutionThe process of dissolving a lyophilized (freeze-dried) peptide powder with bacteriostatic water or sterile water before injection. Proper reconstitution technique is critical — the diluent should be added slowly along the vial wall to avoid damaging the peptide.
DegradationThe breakdown of a peptide through chemical processes like oxidation, deamidation, or hydrolysis. Degredation reduces potency and may produce inactive or harmful byproducts. Proper storage conditions minimize degradation.