Thymopentin Research

Stoica F, Rațu RN, Motrescu I, Râpeanu G, Constantin OE, Cara IG et al.

Tomatoes (Solanum lycopersicum L.) are among the most widely consumed and nutritious vegetables globally, being abundant in lycopene, carotenoids, phenolics, organic acids, vitamins, and several other bioactive and health-enhancing compounds. Tomato processing yields a substantial residue known a...

Haldar S, Kusuma VK, Banerjee S, Misal PR

The current study focuses on optimizing tamarind polysaccharide (TP)/lignin/PVA films incorporated with citric acid. TP (5 g) and PVA (0.875 g) were blended together in a weight ratio of 85% and 15%, respectively. The effects of different concentrations of lignin (0-2 g i.e. 0-40% ...

Zhao N, Yang L, Li T

Abdel-Aziz AM, Ahmed SM, Abdelzaher WY, Mohamed NA, Abdelkader AE, Ahmed RF et al.

Benign prostatic hyperplasia (BPH) is a prevalent urological disorder in aging men, frequently linked to hormonal fluctuations. Agomelatine (AGO), a melatonergic receptor agonist and serotonin 2C antagonist, has demonstrated anti-inflammatory and antioxidant properties. This study aimed to explor...

Zhao X, Yang M, Zhang J, Kong Y, Xu M, Chen R et al.

Background: Current evidence from evidence-based medicine is limited regarding the efficacy and safety of immunotherapy in elderly patients aged 75 years and older with malignant solid tumors. PRaG therapy, which combines PD-1/PD-L1 inhibitors, radiotherapy, and granulocyte-macrophage colony-stim...

Hossain MA, Zhang Y, Ji L, Chen Y, Luan Y, Si Y et al.

Background/Objectives: T cell dysfunction represents a fundamental barrier to effective cancer immunotherapy. Although immune checkpoint blockades and adoptive cell transfer have achieved clinical success, therapeutic resistance remains prevalent across cancer types. Thymopentin (TP5), a syntheti...

Chen X, Ruan Y, Xie J, Huang X, Zhang C, Cui Y et al.

Patients undergoing peritoneal dialysis are at high risk of infection, which significantly impacts morbidity and mortality. This retrospective study aimed to evaluate the association of thymopentin use with infection risk, immune function, and inflammatory markers in peritoneal dialysis patients....

Tang Y, Zhao X, Ding Z, Wang J, Zhang J, Zhou Y et al.

Lipopolysaccharide (LPS), an essential structural molecule in the outer membrane of Gram-negative bacteria, is recognized as a principal trigger of inflammatory responses and oxidative stress. Thus, the control and clearance of LPS is essential to inhibit LPS-induced excessive inflammation, oxida...

Wang Y, Lu H, Xie W, Wang L, Zou Q, Wang S et al.

Indocyanine green (ICG) is a near-infrared dye with photothermal therapy (PTT) and photodynamic therapy (PDT) effects, widely used in cancer treatment. In this study, a multifunctional nanoplatform (ICG-TP-5) was successfully constructed through the supramolecular co-assembly of ICG and TP-5, ena...

Vezzosi Zoto GF, Sacks NA, Urbani MA, Zapata LM

Industrial wastewater pollution is an environmental problem that affects ecosystems and communities. Phycoremediation offers an eco-friendly alternative for contaminant removal. This study evaluated the efficiency of Tetradesmus obliquus (To), Chlorella sorokiniana (Cs), and Chlorella vulgaris (C...

Wang L, Cheng W, Qin S, Tian H, Liu G, Miao P et al.

Cancer cells with stemness characteristics effectively escape the recognition and killing of immune-active cells, such as T cells, which has been considered as the root cause of cancer recurrence and metastasis. To sensitize cancer immunotherapy, we have developed salinomycin-repurposed endoplasm...

Muliya SK, Bindhani UT, Kawlni L, Ramakrishna AK, Mirza V, Rahman MU et al.

The Indian elephant (Elephas maximus indicus), classified as "Endangered" by the IUCN, faces significant population declines and habitat degradation, necessitating robust health assessment tools for both managed and free-ranging populations. This study aimed to establish comprehensive hematology,...

Tahir M, Al-Musabi M, Khaleeq T, Mostafa OES, Dalglish S, Meena A et al.

ACL reconstruction in the paediatric population presents unique challenges, owing to the ongoing skeletal growth. This systematic review aimed to compare the functional and radiological outcomes of transphyseal(TP), partial transphyseal(pTP) and physeal-sparing(PS) techniques.A systematic search ...

Gopinathan A, Sankhe R, Upadhya R, Pai KSR, Kishore A

Neprilysin (NEP) is a neutral endopeptidase that has gained attention due to its ability to cleave diverse peptides such as fibroblast growth factor-2 (FGF-2), insulin-like growth factors (IGFs), substance P, amyloid-β, thymopentin etc. NEP plays an important role in the functioning of the ...

Wang R, Cheng W, Tian H, Dong M, He W, Wang X et al.

Diabetic wounds represent a significant clinical challenge owing to infection, oxidative stress, and immune dysregulation. In this study, a multifunctional photoimmunotherapy nanoplatform (I-P-T NPs) was developed through the self-assembly of the near-infrared photosensitizer IR820, the immunomod...

Park JY, Park WY, Lee B, Song G, Jung Y, Kwak HJ et al.

The traditional medicinal use of Curcumae Radix (CR) and Syzygii Flos (SF) supports the possible application in prostate-related diseases. In this study, we studied the therapeutic effects of CR and SF on benign prostatic hyperplasia (BPH) focusing on the proliferation of prostate cells.We establ...

Sanchez C, Urendes E, Aceves A, Martínez-Olagüe M, Raya R

Psychomotor development, including fine motor skills, progresses throughout childhood and stabilizes in adulthood. This process is closely tied to neurological maturation, with "reaching and pointing tasks" considered fundamental upper limb functions. According to Fitts' law, movement time (MT) d...

Seo D, Lim S, Namgoong B, Uhm H, Hong H, Lee N et al.

To investigate whether point-of-care ultrasound of the external jugular vein (EJV) can predict fluid responsiveness (FR) in healthy, anesthetized, mechanically ventilated dogs.Prospective, nonrandomized experimental study.University-based small animal research facility.Six healthy Beagle dogs.Dog...

Mahajan R, Sarkar R, Panda M, Katakam BK, Padhiyar J, Haritha T et al.

Atopic dermatitis (AD) is the most common inflammatory skin disease in the pediatric age group, affecting 15%-20% of children globally. Initial treatment modes include hydration, occlusive topical medicines, antimicrobial treatment, phototherapy, and systemic immune suppressants in the case of se...

Zhang S, Li Y, Zheng J, Liu C, Diao C, Zhao L et al.

Supramolecular near-infrared (NIR) nanomaterials show great application prospects in cancer photothermal immunotherapy. However, the direct self-assembly of photothermal nanomaterials absorbed in biological transparent window and control over their absorption properties through aggregation behavi...