Protirelin Research

Du P, Peng X, Han H, Kong F, Zhao L, Zhang Z et al.

Managing rutting aggression is critical in sika deer (Cervus nippon) farming. To mitigate rutting aggression in male sika deer, this study evaluated the efficacy, safety, and physiological mechanisms of exogenous progesterone. Twelve sika deer were randomly assigned to either a control group or a...

Uzundere O, Yargı M, Topalel S, Aydın AS, Erbatur ME, Söner HT et al.

Chen J, Zhang X, Chen Y, Lian H, Zhao Y, Song X et al.

Prenatal exposure to bisphenol analogues (BPs) has been suggested to impair fetal growth and increase obesity risk in future life. However, the mechanisms remain unclear. Based on the Shanghai-Minhang Birth Cohort Study, this study aimed to investigate the associations between prenatal exposure t...

Koo TH, Gharib H

Central hyperthyroidism, characterized by elevated thyroid hormone levels with a nonsuppressed thyroid-stimulating hormone (TSH), presents a diagnostic challenge in distinguishing thyroid hormone resistance (RTH) from a TSH-secreting pituitary adenoma (TSHoma).We report a 56-year-old man with a h...

Cengiz G, Küplülü Ö

Bivalve consumption presents a public health risk due to contamination with Vibrio parahaemolyticus, a leading cause of seafood-borne gastroenteritis. This study assessed the occurrence, pathogenicity, antimicrobial resistance, and biofilm-forming ability of V. parahaemolyticus in mussels and cla...

Fry KL, Liu X, Moslehi M, Leeder J, Taylor MP, Martin J et al.

Chemicals are ubiquitous in our homes and gardens. However, the properties that make some chemicals favourable, like medicinal benefits or water repellence, can also make them harmful to human health. This study examined over 100 chemicals in indoor dust, vegetable patch soil and backyard soil (1...

Lang H, Burch K, Sloan D

Mohammadnezhad H, Mohammadi M, Ghaderi A

Downstream scour at grade-control structures (GCSs) poses a serious threat to structural stability and riverbed integrity. Among various countermeasures, riprap has long been recognized as a cost-effective and readily available solution for scour protection. This research examines the role of rip...

McMackin R, Price S, Slator GR, Hardiman O, Kelly JA

There is a pressing unmet clinical and health economic need for effective drugs to treat cognitive impairment that occurs in neurodegenerative diseases. JAK4D is a first-in-class thyrotropin releasing hormone (TRH) analogue that overcomes the pharmacological limitations of thyrotropin releasing h...

Gómez-Morales I, Mendizabal-Ruiz AP, Morales JA, Romero-Gutiérrez T

The Axolotl (Ambystoma mexicanum) offers a deep insight into brain regeneration by fully reconstructing its telencephalon post-injury, a capability that most vertebrates do not have. This study aimed to identify hub genes (highest-weighted genes) underlying this process and to map their cell loca...

Dedeoğlu A, Acil F, Andıç O, Özkılıç M

Background and Objectives: Inadvertent perioperative hypothermia is a common and clinically significant complication during laparoscopic surgery, leading to pain, agitation, shivering, and delayed recovery. This randomized controlled trial evaluated the effect of peri-induction active warming wit...

Otsuka Y, Soejima Y, Nakano Y, Suyama A, Takase R, Oguni K et al.

Long COVID (LC) may involve endocrine dysfunction; however, the underlying mechanism remains unclear. To examine hypothalamic-pituitary responses in patients with LC, we conducted a single-center retrospective study of patients with refractory LC referred to our University Hospital who underwent ...

Meshino H, Uto A, Ishinoda Y, Suzuki K, Oshima N

Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by reversible segmental constriction and dilation of the major cerebral arteries and is typically unrelated to endocrine dysfunction. Central hypothyroidism (CH), a rare form of hypothyroidism caused by insufficient thyroid-sti...

Smith PJ, Blumenthal JA, Ingle K, Watkins LL, Avorgbedor F, Mabe SK et al.

BackgroundTreatment resistant hypertension (TRH) is associated with increased risk of cognitive decline, which may be reduced by healthy lifestyle changes.ObjectiveTo examine the effects of a comprehensive, rehabilitation-based lifestyle hprogram on cognitive function during a one-year follow-up ...

Yanagisawa T, Suzuki E, Araki A, Morozumi S, Yasui K

A 74-year-old man sustained a left femoral neck fracture following a fall on day X. Approximately four hours after the injury, he developed impaired consciousness, which persisted even after osteosynthesis was performed on day X+1. Brain MRI on day X+2 revealed multiple hyperintense lesions scatt...

Zhong R, Fang X, Li C, Zheng B, Zhang G, Gong H et al.

Nanoplastics (NPs) and pathogenic bacteria are widely present in natural water, yet their interactive effects on aquatic organisms remain poorly understood. In this study, we demonstrate for the first time that Vibrio parahaemolyticus can extensively capture free NPs and facilitate their transloc...

Koc ER, Yetkin MF, Saridas F, Turan OF, Sevim S, Terzi M et al.

To evaluate the real-world effectiveness and safety of eculizumab in patients with AQP4-IgG-positive neuromyelitis optica spectrum disorder (NMOSD) and to identify predictors of disability outcomes.This multinational, retrospective cohort study analyzed data from 46 patients across 26 centers. Th...

Cairang Z, Kanasaki H, Tumurbaatar T, S Yacca S, Oride A, Okada H et al.

Prolactin (PRL) plays a variety of roles to maintain female reproductive functions. In female rats, Prl mRNA expression in the anterior pituitary was significantly suppressed by OVX. The OVX-induced inhibition of PRL expression was recovered by estradiol (E2) supplementation after OVX. Supplement...

Asadikaram M, Bahrampour S, Rahimi Naiini M, Jafarzadeh A, Rosen C, Asadikaram G et al.

Prolactin (PRL) is secreted by various cells in the anterior pituitary gland, mammary glands, placenta, uterus, ovaries, testes, skin, adipose tissue, endothelial cells, immune system, and central nervous system. The expression and secretion of PRL are influenced by several factors such as suckli...