Nisin Research

Roddy J, Dhage S, Syed AA

Elnar AG, Jang Y, Eum BG, Hur Y, Huh CS, Kim GB et al.

Lactococcus lactis subsp. lactis DOME 6301, isolated from bovine milk, produces an antimicrobial compound that inhibits oral pathogens including Streptococcus mutans, Prevotella intermedia, and Fusobacterium nucleatum. The entire genome of L. lactis DOME 6301 was sequenced and assembled de novo u...

Hirano Y, Yoshii S, Michida T, Ishihara R

Sidiqa AN, Zakaria MN, Joni IM, Maskoen AM, Cahyanto A

This ex-vivo study aimed to evaluate the antimicrobial effects of calcium hydroxide (Ca(OH)2) nanoparticles combined with nisin against Enterococcus faecalis in infected root canals.The Minimum Inhibitory Concentration (MIC50) and Fractional Inhibitory Concentration (FIC) index were determined to...

Malavasi CV, da Silva EM, Rodrigues FP, Guimarães JGA, Portela MB, Cabral-Oliveira GG et al.

This study evaluated the effectiveness of experimental composites containing antimicrobial agents such as nisin (N) and stannous fluoride (SnF2) against S. mutans, for orthodontic applications. First, the antimicrobial agents were added at varying concentrations (%) into a base material consistin...

Li X, Zhu S, Huang X, Xu Z, Guo T, Kong J et al.

Lacticaseibacillus paracasei (L. paracasei), a probiotic bacterium commonly found in the intestinal tract and fermented products, has been utilized as a tool for generating various bioactive components. However, its potential as a host cell for protein secretion is constrained by the limited avai...

Wang R, Lin Y, Xia Y, Liu S, Feng D, Li S et al.

Antimicrobial resistance poses a serious threat to global food safety and poultry production, prompting the need for effective alternatives to conventional antibiotics in food-producing animals. In this study, a recombinant food-grade strain, L. lactis NZ-BB, was engineered to express a fusion an...

Wang Z, Yang C, Zhang R, Yang W, Hu Y

To enhance fruit preservation efficacy, nisin (NIS) was encapsulated within zeolitic imidazolate framework-8 (ZIF-8) to form a ZIF-8/NIS composite. This composite was integrated into polycaprolactone/chitosan (PCL/CS) nanofibers via electrospinning (ELS), fabricating active packaging membranes. C...

Kesmen Z, Batman SG, Canpolat M, Büyükkiraz ME

In this study, we aimed to develop a novel antimicrobial peptide (AMP) design strategy via a localization-based motif combination approach to target Gram-negative and Gram-positive pathogenic bacteria. Peptide sequences with high inhibitory activity against Escherichia coli and Staphylococcus aur...

Xing W, Liu W, Yang B, Fan L, Zhou Y, Wang Z et al.

To mitigate environmental pollution and food contact safety concerns associated with traditional non-biodegradable plastic packaging, biodegradable and edible polysaccharide-based materials such as bacterial cellulose (BC) can serve as an ideal alternative for food packaging. In this paper, BC/Ni...

Liu L, Huang Y, Xu H, Sun Y, Xu ZZ, Huang X et al.

Diabetic vascular complications (DVCs) are a major cause of morbidity in diabetes, with gut microbiota dysbiosis emerging as an important contributor. This study investigates the impact of nisin, a widely used food preservative, on DVCs using a zebrafish model. We found that nisin exacerbates dia...

Meskhi B, Todorov SD, Rudoy D, Olshevskaya A, Shevchenko V, Maltseva T et al.

Modern agriculture faces the critical need to develop sustainable, safe, and effective strategies for enhancing productivity, protecting plants and animals, and ensuring food security. Challenges posed by antibiotic resistance and the adverse environmental and consumer health impacts of chemical ...

Carvalho de Paula AE, Silva Siqueira C, Lorenzón EN

Oral cancer represents a significant cause of mortality and morbidity, especially when discovered late. Microbial infections, particularly those caused by Porphyromonas gingivalis and Fusobacterium nucleatum, play a crucial role in cancer development and prognosis, especially in the oral cavity. ...

Wang P, Ma Y, Wu J, Xu J, Zhang B, Huang Q et al.

Bacillus cereus 0-9 is a biocontrol strain with abundant antimicrobial peptide (AMP) biosynthesis gene clusters. This strain exhibits significant antibacterial activity against Gram-positive bacteria. Notably, the deletion of gene abrB, encoding global transcriptional regulator AbrB, resulted in ...

Zeng X, Yu C, Chen X, Liu Z, Li J, Yan S et al.

The problem of swollen canned Hubei broad bean paste, a traditional fermented food, leads to significant quality degradation and economic loss. This study aimed to isolate and identify the causative gas-producing bacterium and develop an effective control strategy. A dominant strain, designated C...

Baranidharan S, Perasiriyan V, Ramkumar R, G S, S A

Pearl millet (Pennisetum glaucum), a vital cereal crop widely cultivated in the arid and semi-arid regions due to its remarkable tolerance to drought, high temperature, and poor soil fertility. More prominently, these grains are rich in carbohydrates and high proportion of starch, which tends to ...

Hongkulsup C, Kumchun T, Wilasuwan T, Javadi B, Cutter CN, Pattanayaiying R et al.

In this study, a novel antimicrobial bilayer film was developed to enhance the shelf-life of raw meat and poultry. The film comprised a fish skin gelatin bottom layer with excellent water absorption capacity and a pullulan top layer incorporating lauric arginate and/or nisin Z, which are both Gen...

Cabuhat KSP, Tan TVC, Ong CJN, Mortel FA, Bacalzo GD, Nuevo JJM et al.

Antimicrobial resistance (AMR), particularly in methicillin-resistant Staphylococcus aureus (MRSA), continues to threaten global health due to its multidrug resistance and strong biofilm-forming ability. Antimicrobial peptides (AMPs) have emerged as promising agents against MRSA biofilms because ...

Sánchez-Ceja MG, Esquivel-Alejo JL, Medina-Estrada RI, Jiménez-Mejía R, Santoyo G, López-Meza JE et al.

Mastitis is one of the major diseases affecting dairy cattle worldwide. Antibiotic therapy remains the most widely used treatment. However, its effectiveness has been compromised due to the selection of antibiotic-resistant and biofilm-producing pathogenic bacteria. This promotes the search for a...

Zhuang Y, Li Y, Wang B, Fei P, Huang B, Zhang Q et al.

To enhance the antibacterial properties of chitosan, this study employed papain as a biocatalyst to graft nisin onto chitosan, yielding two grafted products with grafting ratios of 8.56% (Ni1-Cs) and 14.35% (Ni2-Cs). Structure analyses confirmed the formation of amide bonds. Grafting significantl...