MGF Research

Weberling LD, Ochs A, Aus dem Siepen F, Salatzki J, Haney AC, Giannitsis E et al.

Unlike systolic heart function, the assessment of diastolic heart function is often demanding using cardiovascular magnetic resonance (CMR) imaging. This study aims to assess the value of semi-automatic CMR-derived biplane functional parameters in patients with cardiac light chain (AL) and transt...

Sardão BG

This reflective piece explores the impact of childhood experiences with elderly family members on the development of empathy. The author connects these formative experiences to her evolving role as a family physician, emphasizing the importance of presence, attentiveness, and emotional insight wh...

Liu H, Sun L, Wang F, Huang X, Huang J, Kang X et al.

African swine fever (ASF) is a highly contagious viral disease caused by the African swine fever virus (ASFV), which primarily affects pigs. ASFV encodes a variety of proteins that contribute to immune evasion, with the mechanisms of immune escape being diverse, complex, and not yet fully underst...

Martín-Noguerol T, López-Úbeda P, Barrientos-Manrique EA, García-Ferrer M, Luna A

Staging gynecological malignancies is a complex process, and radiologists should be familiar with the evolution of FIGO staging criteria. Large Language Models (LLMs) offer potential to support radiologists by automating classification tasks from free-text MRI reports.We conducted a retrospective...

Li Y, Wu LS, Lyu MT, Li Y, Wang TS, Xu FQ et al.

Fatty acid synthase (FASN), which is highly expressed in multiple cancers, contributes critically to cancer cell survival, proliferation, and metastasis, rendering it a promising target for therapeutic intervention. To develop novel and efficient FASN inhibitors, a series of lipophilic amide frag...

Alobid I, Seys SF, de Kinderen J, Hox V, Cavaliere C, Andrianakis A et al.

The SYNAPSE phase 3 study demonstrated that mepolizumab significantly improves nasal polyp score (NPS), quality of life and symptom severity in patients with chronic rhinosinusitis with nasal polyps (CRSwNP).We aimed to evaluate mepolizumab effectiveness in a real-world cohort from 12 tertiary ce...

Harduin L, Cortizo L, Filippo MG, Barroso TA, Guerra JB, Mello RS et al.

To evaluate arteriovenous fistula maturation and 12-month patency in patients undergoing oversized balloon angioplasty with high-pressure balloons alone or with high-pressure balloons plus drug-coated balloons as part of endovascular treatment for arteriovenous fistula maturation failure.This pro...

Ni Z, Wei B, Zeng Y

Drug-target affinity (DTA) prediction is one of the core components of drug discovery. Despite considerable advances in previous research, DTA tasks still face several limitations with insufficient multi-modal information of drugs, the inherent sequence length limitation of protein language model...

Li X, Zhang L, Qiu W, Xu X, Xiao X, Nan J et al.

As a pivotal component in sodium-ion batteries (SIBs), the separator critically governs interfacial stability and ion transport efficiency. Herein, an interface engineering strategy is proposed for constructing a high-performance polyimide-based separator modified with a nano-MgF2 coating via a f...

Dai Y, Huang Q, Tan M, Wang Z, Jiang C, Liu Z et al.

Mangiferin (MGF) is a natural C‑glucosyl xanthone with multitarget activity relevant to metabolic, inflammatory and cancer diseases. Notably, MGF modulates AMP‑activated protein kinase, NF‑κB, PI3K/AKT and MAPK signaling; through these pathways, it affects glucose and l...

Xu Z, Li W, Yan Y, Gao Q, Wang T, Dun H et al.

Dopant-free materials with wide-bandgap are promising alternatives to n-type or p-type amorphous silicon (a-Si) contacts in silicon heterojunction (SHJ) solar cells. They offering strong carrier selectivity through favorable band alignment, negligible parasitic absorption, and full compatibility ...

Wu Y, Cai Z, Zhang Y, Zheng Y, Liao L, Jia Z et al.

Infected bone defects (e.g., osteomyelitis) present a complex clinical challenge characterized by persistent biofilms, intracellular pathogens, and compromised bone regeneration. We hypothesized that a bioadaptive magnesium implant with sequential coating/substrate degradation could render staged...

Wang N, Sun Z, Chen F, Tian X, Li J, He X et al.

Studies have demonstrated that accumulation of formaldehyde (FA) in the body can result in Alzheimer's disease (AD) like changes including cognitive impairment, Aβ deposition, and Tau hyperphosphorylation. Mangiferin (MGF), a natural flavonoid compound, has been suggested in previous r...

Narvai PC, Soares CCDS, Frias AC, Antunes JLF

To analyze the non-exclusive impact of community water fluoridation on the prevalence of caries and dental fluorosis in schoolchildren in the municipality of São Paulo between 1986 and 2023.Secondary data were used for the index age of 12 years, provided by the Ministry of Health, covering c...

Yang C, Mao W, Dong X, Tian S, Shen J, Zhang W et al.

Hydrogen-assisted dehydrochlorination process (HaDHC) is an attractive route for the production of fluorine-containing olefins under relatively mild conditions, so far lacking the highly efficient metal-based catalysts and their design strategy. Here, we report a nano-MgF2 supported Pd-Ag catalys...

Xu MB, Hu YX, Wang MC, Li JJ, Lian JM, Chen J et al.

Birefringent crystals are essential optical materials for modulating and detecting the polarization state of light. However, achieving large optical anisotropy remains a significant challenge, mainly because it is difficult to rationally align anisotropic fundamental building blocks (FBBs) to max...

Shiel EV, Miah J, Chattopadhyay T, Rauf A, Dalton C, Husain N et al.

South Asian populations in the UK experience increased health risks related to long-term conditions, exacerbated by underdiagnosis, cultural differences in help-seeking behaviours, language barriers, low health literacy and a lack of culturally sensitive services. We know that group interventions...

Arslanhan G, Taşdemir Mete ME, Sargın M, Baştopçu M, Selçuk N, Arslanhan Aylin Ş et al.

Intraoperative transit time flow (TTF) measurement provides quantitative information regarding graft patency and anastomotic quality. However, limited data exist on the relationship between SYNTAX scores and intraoperative graft flow dynamics during coronary artery bypass grafting (CABG). This st...

Ribeiro L, Pereira HABDS, Trevizol JS, Delgado AQ, Cestari TM, Buzalaf MAR et al.

Fluoride is commonly used in dentistry to prevent dental caries, however, excessive exposure may pose risks to soft tissues, particularly the kidneys, which are responsible for approximately 60% of fluoride excretion. Diabetic nephropathy, a major complication of diabetes mellitus, may share path...

Wang Y, Kim JH, Yonezawa S

Fluorination has been proposed as an effective surface modification method for magnesium. The high-temperature oxidation behavior and protective mechanism of fluorinated AZ31 magnesium alloys, especially under prolonged isothermal conditions, have not been systematically investigated. In this stu...