Hexarelin Research

Wu YH, Guo C, Ye ZR, Hu XL, James TD, Li J et al.

Ever-increasing evidence confirms the role of O-GlcNAcase (OGA) in mediating cell growth and development as well as pathology and underscores the importance of developing sensitive and selective chemical tools for the study of OGA biology. Here, based on our previously developed protein-encapsula...

Umpleby B, Hex N, Martins T, Soori H

The existing intravenous systemic anticancer therapy (SACT) pathway in pharmacies is operationally inefficient. Manual, paper-based workflows render the system prone to human error, and the need for time-consuming manual verification diverts pharmacy staff time. The introduction of an automated w...

Shereif AS, Heikal MTS, El Ela ASA, El Shabasy A, Masoud AE, Csámer Á et al.

Granitic rocks constitute one of the most prevalent and economically significant lithologies, owing to their abundance, mechanical durability, and aesthetic appeal, which render them highly suitable as ornamental stones in architectural and construction applications. In recent years, extensive re...

Ruan J, Zhang P, Cheng J, Yu L, Wu Y, Zheng Y et al.

Two glycans, ZJPr2-2-1 and ZJPr3-2-1, were isolated from jujube fruits. Structural analysis revealed ZJPr2-2-1 (7.20 kDa) as a previously unreported pectin featuring main chain of →4)-α-D-GalpA-(1→, →3,4)-α-D-GalpA-(1→, and →3)-α-L-Rhap-(1...

Qin Z, Zhou Q, Wu RK, Houk KN

We employed density functional theory, CCSD(T) and CASSCF computations, along with quasi-classical molecular dynamics simulations, to explore the ring opening of bicyclo[2.2.0]hex-2-ene and its 1-amino-4-cyano derivative. While the overall reaction is a formally forbidden 4-electron disrotatory e...

Aryal B, Acharya S, Sitaula S, Karki P, Chaudhary M

To access and compare the corneal endothelial morphology between type two diabetic patients (T2DM) and non-diabetic controls, and to explore their associations with diabetes duration, HbA1c levels and severity of diabetic retinopathy in a Nepalese cohort as diabetes can lead to morphological chan...

Elzami R, Becker A, Block J, Doitch O, Livne S, Levratovsky S et al.

To assess the adhesive bond strength of two provisional screw-retained computer-aided design and computer-aided manufacturing (CAD-CAM) crowns bonded to titanium bases (TiB) following artificial aging, tensile testing, and failure mode analysis.Ninety CAD-CAM hybrid abutment crowns (HAC) were eva...

Wang Y, Luo P, Xu H, Zhan L, Sakamoto K, Li M et al.

The alarming rates of deaths due to opioid overdose present an urgent need for safer opioid analgesics. Positive allosteric modulators (PAMs) of opioid receptors (ORs) offer a promising approach to enhance opioid efficacy while reducing risks of overdose. In this study, we unveil the selective me...

Biebl SM, Lienert JN, Müller AJ, Ströbele M, Dreuw A, Wachtveitl J et al.

Derivatives of 1,2-dihydro-1,2-azaborinines generally undergo selective photochemical electrocyclic ring-closure reactions to the corresponding Dewar isomers (2-aza-3-borabicyclo[2.2.0]hex-5-ene). Depending on the substitution pattern, these photoreactions can also yield benzvalene (3-aza-4-borat...

Panji M, Modarresi MH, Azizi Z, Absalan M, Motevaseli E

 Gold nanoparticles (AuNPs) have demonstrated promise in enhancing polymerase chain reaction (PCR) efficiency, leading to more precise viral detection. The integration of AuNPs into PCR protocols has been shown to improve amplification efficiency and detection specificity, thereby enabling m...

Bao L, Jin L, Yang Y, Zhao Y, Wu K, Shan R et al.

Hexadecanamide (HEX) has been recognized for its significant anti-inflammatory properties. However, its specific role and underlying mechanisms in the context of colitis remain poorly understood.Herein, we first determined the effect of oral HEX on DSS-induced colitis in mice. Our results showed ...

Lin X, Rong X, Xie J, Wang X, Wang J, Xu Z et al.

The strength-ductility trade-off in oxygen-containing titanium alloys has long been limited by the embrittling nature of octahedral interstitial oxygen (oct-O). Herein, by integrating controlled laser powder bed fusion (L-PBF) processing with Cu─O co-alloying, we achieve, for the first tim...

Mphaga KV, Rathebe PC

This systematic review and meta-analysis evaluated the environmental radioactivity associated with mining operations across Africa. It included 26 studies published between 2010 and 2025. A subgroup meta-analysis revealed that regions impacted by mining exhibit significantly elevated activity con...

Faraj TK, Gawad AEA, Khandaker MU, Hanfi MY

This study presents an integrated geological and environmental radiological analysis of basaltic volcanic rocks, which have been characterized by their suitability and potential for risk when used as construction materials. A total of thirty-five representative basaltic samples from the environme...

Volkova T, Simonova O, Perlovich G

Background/Objectives: Advancing information on the key physicochemical properties of biologically active substances enables the development of formulations with reduced dosing, lower toxicity, and minimal adverse effects. This work addresses the knowledge gap concerning the pharmacologically rel...

Bobrova EA, Skorotetсky MS, Kuleshov BS, Gaidarzhi VP, Trul AA, Agina EV et al.

An efficient synthetic method for the preparation of self-assembling conjugated organic materials with a silazane anchor group based on direct hydrosilylation reaction is reported. A novel organic semiconductor molecule, NH(Si-Und-BTBT-Hex)2, consisting of a polar silazane anchor group linked thr...

Wang GY, Li YY, Zhang M, Liu J, Wang F, Chen L et al.

The Hoplia spectabilis (Coleoptera: Scarabaeidae) is a major pest threatening local shrubs in the plateau ecosystems of western China. However, little information is available on its chemical ecology. In this study, we aimed to identify host-plant volatiles used for host location by Hoplia specta...

Singh A, Sarkar A, Pokarram SS

Accidental ingestion and aspiration of dental instrument are an infrequent finding in dental practice settings, although at times inadvertently it can happen. The location of the ingested/aspirated object should be confirmed first, followed by adequate intervention. Radiographic examination will ...

Nevin J, Suffield C, Mutch S, Glass M, Sadler S, Mclay W et al.

Nevin, J, Suffield, C, Mutch, S, Glass, M, Sadler, S, Mclay, W, Coonan, L, Glass, M, Sadler, S, Penver, R, and Beckingham, J. The effectiveness of a 10-week concurrent strength and endurance training program on the physical readiness of trained British Army soldiers. J Strength Cond Res 40(2): e1...

Hao M, Zhang Z, Lai X, Cao J, Zhang S, Li Q et al.

Preliminary tossing, a novel step inserted before conventional oolong processing, was evaluated for its ability to enhance the aromatic compounds of high-flavor oolong tea. But the preliminary tossing of promoting the conversion and release of aroma substances is not clear. Preliminary tossing si...