Carperitide Research

Sakai M, Hishida E, Ogura M, Masuda T, Ogoyama M, Imai T et al.

Managing pregnancy in patients with end-stage kidney disease (ESKD) undergoing dialysis is challenging, with hypoalbuminemia significantly increasing risks to both maternal and neonatal outcomes. Intensive hemodialysis regimens are recommended; however, individualized and adaptive dialysis strate...

Zhang S, Song M, Zhang J, Bai J, Cao X, Zhu L et al.

Uveal melanoma (UM) is the most common primary intraocular malignancy in adults and is highly aggressive, with no therapies shown to improve overall survival. Although immunotherapy achieves response rates of 33-40 % in advanced cutaneous melanoma, its efficacy in UM is disappointingly low...

Shiga T, Suzuki A, Inoue S, Hashiguchi M

Carperitide, which is an α-human A-type natriuretic peptide, is used intravenously for the treatment of acute heart failure (AHF) primarily in Japan. However, its clinical effectiveness has not been established. The aim of this meta-analysis was to assess the effect of carperitide on the cl...

Abushowmi T, Alalawi H, Abualsaud R, Alramadan D, Ayad NM, Akhtar S et al.

This study aims to evaluate and compare the effect of the addition of two nanoparticles (silicon dioxide [Si-NPs] and hydroxyapatite [HA-NPs]) on the flexural strength and surface properties of three-dimensionally (3D)-printed denture base materials.In this study, Si-NP and HA-NP were added separ...

Azaryan E, Ghodousi A, Hanafi-Bojd MY, Naseri M

In this study, we investigated the potential of hydroxyapatite nanoparticles (HA-NP) synthesized from Elaeagnus Angustifolia (HAEA-NP) and loaded with crocin (HAEA-NP@CR) to enhance the in vitro wound healing of human dermal fibroblasts (hDF).HAEA-NPs were synthesized using the sol-gel technique ...

Khan A, Rath S, Waqas SA, Alam U, Ali MA, Khadim S et al.

Acute heart failure (AHF) is a common and severe condition associated with high morbidity and mortality. Carperitide, a recombinant human atrial natriuretic peptide, has been widely used in Japan for managing AHF. However, its effectiveness in improving clinical outcomes such as mortality rates r...

Ayaz Z, Alsarkhi LN, Rawat A, Aqel Y, Mazhar M, Chaudhari SS et al.

Heart failure remains a leading global health burden affecting over 64 million individuals worldwide, with limited effective acute management strategies. Carperitide, a recombinant form of human atrial natriuretic peptide, has been primarily used in Japan for acute heart failure treatment, but it...

Monette CE, Lee J, Peasah A, Sayles LC, Tai M, Sweet-Cordero EA et al.

Biomaterials-based 3D models have emerged as new cancer research tools for studying osteosarcoma (OS). However, the impact of scaffold material choice on OS phenotype and drug responses in 3D remains largely unknown, as previous studies used different biomaterials as scaffolds without direct comp...

Alhamdan EM

Impact of different pretreatment regimes i.e., Hydrofluoric (HF) acid, ytterbium fiber laser (YFL), Malachite green (MG) activated low level laser therapy (LLLT) on the surface topography, contact angle, and shear bond strength (SBS) of Lithium disilicate ceramic (LDC) bonded to 1 % hydroxyapatit...

Zhang Y, Wu Y, Xie Y, Liu G, Wang S

Immunotherapy has emerged as a new strategy for tumor suppression, but its effectiveness is restricted by the immunosuppressive tumor microenvironment (TME) in the context of osteosarcoma treatment. Therefore, a series of therapies focused on immune activation have been introduced as combination ...

Zhang L, Liu T, Chen M, Gao S, Staley CA, Yang L et al.

Metabolic reprogramming characterized by mitochondrial dysfunction and increased glycolysis is associated with aggressive tumor biology and poor therapeutic response. The interplays among NADPH oxidase (NOX)-mediated reactive oxygen species, regulation of glycolysis and oxidative phosphorylation ...

Li S, Yang R, Zhao Z, Xie M, Zhou Y, Zeng Q et al.

Hydroxyapatite nanoparticles (HANPs) are well-known nanomaterials for bone regeneration or repair. In recent years, HANPs have emerged as a potential tool in tumor therapy because of the numerous advantages the nanoparticles offer, including the diverse physicochemical properties, the selective a...

Abdullah Kamran M

Effects of contemporary remineralization agents on the repair and regeneration of eroded enamel, specifically examining Vickers hardness (VH), shear bond strength (SBS), the calcium/phosphorus (Ca/P) ratio, and bracket-enamel interface.Extracted maxillary premolars with intact enamel were selecte...

Izumi K, Utsunomiya H, Tohgi K, Takeuchi M, Hamada A, Hyodo Y et al.

Atrial fibrillation (AF) may cause right-sided heart remodeling such as tricuspid valve annular (TVA) dilatation, leading to atrial functional tricuspid regurgitation with prognostic impact. Not all AF patients develop TVA dilatation; therefore, predicting its occurrence is challenging. This stud...

Gültekin A, Uğur A, Sulak M, Demirezen S, Yüksel D

Radiolabeling of nanoparticles has potential benefits for personalized treatments and theranostic applications, which have been on the agenda in recent years. Hydroxyapatite nanoparticles (HANP), which have a great similarity to bone tissue, stand out as a biocompatible nanoparticle. The differen...

Sornamalar M, Dhanavel C, Balavaishnavi G, Shajahan S, Baskar K, Raja SV et al.

To optimize a novel composite scaffold comprising of nano phosphorylated pullulan incorporated carboxymethyl chitosan (nPP-CMC) and to evaluate its cell viability and proliferation in human dental pulp stem cells (hDPSCs).Nano phosphorylated pullulan (nPP) in concentrations of 200 mg, 400 mg, 600...

Honda S, Nagai T, Honda Y, Nakano H, Kawabata T, Maeda H et al.

The effects of low-dose carperitide on long-term clinical outcomes of patients with acute heart failure (AHF) have not yet been fully elucidated. This study aimed to evaluate the effects of low-dose intravenous carperitide on the long-term clinical outcomes of patients with AHF.In this multicentr...

Dong W, Mau M, Soule S, Sato E, Thorne T, Higgins T et al.

To compare outcomes after ankle fracture fixation between those receiving formal physical therapy (PT) versus no formal PT and those with high versus low patient-reported outcome measurement information system (PROMIS) anxiety score (AS), and to evaluate the effect of PT in the setting of PROMIS ...

de Melo EL, Miranda JM, Lima VBSR, Gaião WDC, Tostes BVA, Rodrigues CG et al.

To evaluate in vitro the effect of laser photobiomodulation (PBM) combined or not with 30-nm hydroxyapatite nanoparticles (HANp), on the osteogenic differentiation of human umbilical cord mesenchymal stem cells (hUC-MSCs) by morphometric analysis using artificial intelligence programs (TensorFlow...

Yanagawa T, Asai Y, Zakoji N, Hosoe S, Kondo Y, Ootsuki S et al.

Sacubitril/valsartan is an angiotensin receptor neprilysin inhibitor (ARNI) that inhibits the degradation of endogenous natriuretic peptides. Therefore, ARNIs may increase the efficacy of human atrial natriuretic peptide (hANP), a drug for acute heart failure, by mediating its pharmacological mec...