Carbetocin Research

Binyamin Y, Kviat K, Heesen P, Azem K, Assor EL, Frenkel A et al.

Oxytocin is widely used for prevention of postpartum hemorrhage, whereas carbetocin provides a longer uterotonic effect. We compared their effectiveness as routine prophylaxis during cesarean delivery.We conducted a retrospective before-and-after cohort study at a single academic center. Women un...

Samimi M, Hosseiniara R, Akbari H, Beyrami D

Miggelbrink LA, Nijman TAJ, Megens JHAM, van den Bosch OFC

Turner WJ, Boonstra L, Maxwell C, Downey K, Balki M

M Sethuraman R

Maged A

Đuričić D, Samardžija M, Zobel A, Szenci O, Zobel R

The study evaluated the effects of denaverine hydrochloride (DH) and carbetocin (CT) on calving ease and subsequent fertility in suckler cows. A total of 242 cows were enrolled in a blinded study and assigned to four groups with different treatment protocols: Group A (DH + CT), Grou...

Pathak N, Jadhav VM

Prevention of postpartum hemorrhage is imperative due to its impact on maternal morbidity and death. Uterine atony is regarded as the predominant cause of postpartum hemorrhage. Preventive use of uterotonic agents is one of the most important steps in the active management of the third stage of l...

Deshpande H, Patel S, Pojala RP, Dhediya R, Saha S

Postpartum hemorrhage (PPH) remains a leading cause of maternal morbidity and mortality worldwide. Timely placental separation and effective uterotonic therapy are critical components in the prevention and management of PPH. Oxytocin has been the gold standard for uterotonic use; however, newer a...

Grahofer A, Nathues H, Becker J

An aceptable target range for stillbirths per litter varies between 5-7% of total born piglets in sows. Several major risk factors have been identified that contribute to the increased incidence of stillbirths in piglet-producing herds, including the use of uterotonic agents. Oxytocin and carbeto...

Zhang Y, Hao M, Hu Y

Patients with schizophrenia (SCZ) exhibit a significantly higher prevalence of metabolic syndrome (MetS), suggesting a potential biological link between the two conditions. However, the molecular mechanisms underlying this comorbidity remain unclear. This study aimed to identify shared molecular ...

Canto-de-Souza L, Baptista-de-Souza D, Busnardo C, Crestani CC

We investigated the effect of systemic administration of the synthetic oxytocin (OXT) analog carbetocin and/or OXT receptor antagonists (atosiban and L-368,899) on social avoidance and anxiogenic-like effect in male rats subjected to chronic social defeat stress (cSDS). Effect of cSDS and pharmac...

Bekkenes ME, Jørgensen MM, Jacobsen AF, Fagerland MW, Rakstad-Larsen H, Aaberge L et al.

Kahyaoğlu B, Temoçin RB, Güçlü M, Kırlangıç MM, Sayın EÜ, Özkul A et al.

To evaluate the comparative effectiveness of four pharmacologic regimens - oxytocin, carbetocin, oxytocin plus tranexamic acid (TXA), and carbetocin plus TXA - for postpartum hemorrhage (PPH) prophylaxis in cesarean deliveries.This prospective cohort study was conducted at a t...

Mishra N, Darji P, Singh A, Mitra N, Mishra D

We aim to determine the comparative effectiveness of heat-stable carbetocin (HSC) versus oxytocin for the prevention of atonic postpartum haemorrhage (PPH) at a tertiary care centre in Central India.This study is a prospective observational study conducted over 18 months (January 2023 t...

Zagrodnik E, Szczuko M, Kordek A, Surówka A, Szydłowska I, Rzewuska B et al.

Background/Objectives: The aim of this study is to analyze the frequency and type of subjective adverse events reported after the use of oxytocin and carbetocin in women giving birth by cesarean section. Methods: A total of 70 pregnant women, previously scheduled for elective cesarean section, we...

da Silva Kazitani Cunha M, Barbosa LM, de Moraes Bastos Gonçalves MB

Elmas B, Zorlu U, Türker Ergün G, Turgay B, Salman-Özgü B, Karagöz Ç et al.

This study compares the effectiveness and safety of three prophylactic uterotonic regimens-intravenous carbetocin, oxytocin infusion, and oxytocin-ergometrine combination-in preventing postpartum hemorrhage (PPH) in women with isolated polyhydramnios.This retrospective cohort study included 286 t...

Baştemur AG, İpek G, Yıldız EG, Habibi Z, Tanaçan A, Kara Ö et al.

This study aimed to compare the effectiveness of oxytocin and carbetocin in preventing postpartum hemorrhage, based on hemoglobin changes between the preoperative and 6-h postoperative periods, operating time, and postoperative shock indices.This retrospective cohort study was conducted on single...

Martínez-Hernández J, Garriga F, Ahmad A, Padilla L, Maside C, Bonet S et al.

The oxytocin receptor (OR) is a G-protein-coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown.In this study, using the pig as a model, we examine the presence of the OR in ejaculated spermatozoa through immunofluorescence and immunob...