Buserelin Research

Lemos LA, Carvalho LR, Vicente MP, Souza Simões LM, Fernandes do Vale LS, de Souza JC et al.

The objective was to evaluate the fertility of Bos indicus cows submitted to an ovulation synchronization protocol without estrogen (E2). In experiment 1, injectable P4 (P4i) was administered 10 days (D-10) before the TAI protocol. On D0, cows received one intravaginal P4 device and estradiol ben...

Tosi F, Zanolin ME, Garofalo S, Gremes V, Zoppini G, Moghetti P et al.

Impaired insulin clearance has been found in women with PCOS and contribute to generate hyperinsulinemia in these subjects. However, the mechanisms underlying this phenomenon remain unknown. The aim of this retrospective study was to explore if the heterogeneous treatments used in these patients ...

Enatsu N, Furuhashi K, Otsuki J, Enatsu K, Okamoto E, Kokeguchi S et al.

To investigate the optimal timing for triggering oocyte maturation by evaluating the interval from the trigger to oocyte retrieval and the subsequent in vitro fertilization outcomes. The administration of human chorionic gonadotropin (hCG) or gonadotropin-releasing hormone agonist (GnRHa) is a cr...

Rohde Brondani L, Martini AP, Rohde Brondani C, Dos Santos Brum D, Pessoa GA, Gallas Leivas F et al.

The aim of this study was to evaluate the use of buserelin acetate, a GnRH analog, in combination with estradiol benzoate (EB) at the beginning of an early resynchronization protocol (R22) in Bos taurus beef heifers. A total of 656 heifers underwent a first fixed-time artificial insemination (FTA...

Léo AMP, de Moraes FP, Rovani MT, Ferreira R, de Sousa Sales JN, Mondadori RG et al.

Timed artificial insemination (TAI) protocols in South America are mainly based on progesterone (P4) and estradiol (E2). Considering the restrictions on E2 use, the study aimed to evaluate its replacement with GnRH. Multiparous suckling Bos taurus cows (n = 455) were pre-synchronize...

Taechamaeteekul P, Boonyarattanasoonthorn T, Srisang C, Adi YK, Dumniem N, Singlor J et al.

Buserelin acetate, a synthetic analog of gonadotropin-releasing hormone (GnRH), is used to induce ovulation and enable fixed-time artificial insemination (FTAI) in swine. Evaluating the pharmacokinetics of buserelin acetate is crucial for optimizing its application in precisely controlling ovulat...

Benvenga S, Russo M, Famà F, Forte G, Unfer V

We compared 37 women with polycystic ovary syndrome (PCOS) with 24 women with eumenorrhea plus hyperandrogenism and/or hyperandrogenemia without ultrasound evidence of PCO morphology (EuHyperA) to assess their hormone responses to a GnRH-agonist (buserelin). Following our recent paper on PCOS and...

Tschopp JC, Menchaca A, Bó GA

The aim of this study was to compare pregnancy per AI (P/AI) in resynchronization (Resynch) protocols using different hormonal combinations (estradiol benzoate [EB], a double dose of GnRH, or EB with a double dose of GnRH) administered on the day of progesterone (P4) device insertion. We hypothes...

Noleto GS, Silva SA, Barbosa IP, B Siqueira LG, Gasperin BG, Rovani MT et al.

The objective of the present study was to evaluate whether the inclusion of a gonadotropin-releasing hormone (GnRH) treatment at a novel time (34 h) after intravaginal progesterone device (IPD) removal improves ovulation synchrony and increases fertility in crossbred Girolando dairy cows (...

Uddin AM, Kirkwood RN, Petrovski KR, Youssef SH, Singh B, Mukhopadhyay S et al.

Background/Objectives: This study aimed to enhance the vaginal permeation of buserelin acetate (BA), a synthetic gonadotropin-releasing hormone (GnRH) analogue, by evaluating various permeation enhancers (PEs) using a validated reversed-phase high-performance liquid chromatography (RP-HPLC) metho...

Castillo JJ, Vicente JS, Marco-Jiménez F, Aguilar E, Viudes-de-Castro MP

This study evaluated the effectiveness of a 3D-printed cannula in inducing ovulation in female rabbits without exogenous GnRH analogues. A total of 325 inseminations were performed across different physiological stages: nulliparous, multiparous lactating, and multiparous non-lactating does. Two i...

Buda K, Vegi B, Varadi EK, Drobnyak A, Török E, Szabo Z et al.

Orthotopic transplantation of ovarian tissue at one day of age is a promising solution for preserving female genetic material in avian species; using sterile recipients can ensure that all offspring are donor-derived. This study focuses on the suitability of the Mulard duck as a sterile recipient...

Sawant S, Tulsyan S, Homburg R

Gonadotropin-releasing hormone agonist (GnRHa) trigger is widely used in IVF/ICSI to reduce ovarian hyperstimulation syndrome (OHSS) risk, particularly in women with polycystic ovary syndrome (PCOS). However, the endocrine response is variable, and a threshold post-trigger luteinizing hormone (LH...

do Couto SRB, Caparelli NMPM, Costa MG, Guerson YB, Lamim RA, Vidal RS et al.

This study aimed to evaluate the relationship between the body condition score (BCS), pre-ovulatory follicle (POF) and corpus luteum (CL) characteristics, progesterone (P4) concentrations, and reproductive success in Nellore cows subjected to timed artificial insemination (TAI). Two strategies we...

Kasamawut K, Udduang S, Kattakdad S, Danwandee K, Jutagate A, Saowakoon S et al.

Fishes of the genus Rasbora in the Cyprinidae family comprise 88 species [...].

Chen Y, Lu W, Liao R, Zhang X, Chen W, Wang J et al.

Long-acting Gonadotropin-releasing hormone analogs(GnRHa), including leuprolide, goserelin, histrelin, buserelin, triptorelin, have been widely used for a variety of diseases including prostate cancer, breast cancer, endometriosis, uterine leiomyomas, and central precocious puberty (CPP). However...

Shi Z, Wang Z, An L, Li Z, Cheng L, Yue Y et al.

Fixed-time artificial insemination (FTAI) is currently a standardized protocol for pig reproductive management. Efficient ovulation synchronization induced by GnRH analogs is critical for ensuring the pregnancy outcomes of FTAI. However, among the widely used GnRH analogs, the degree of synchroni...

Taechamaeteekul P, Adi YK, Suwimonteerabutr J, Sang-Gassanee K, Lin H, Collell M et al.

Administering exogenous GnRH at the onset of standing estrus induces ovulation within ∼37.5 ± 3.3 h by stimulating LH secretion, narrowing the optimal insemination window. This study evaluated the effects of supplementing extended boar semen with a GnRH analog (busereli...

Gallelli MF, Bianchi C, Zampini E, Aba M, Rodriguez M, Neild D et al.

This study aimed to evaluate the effect of hCG injection on Day 3, 4 or 5 post-induction of ovulation on corpus luteum (CL) function in llamas and then, to evaluate its effect on pregnant animals. After induction of ovulation with buserelin (Day 0), llamas were randomly assigned to one of four gr...

Alves RLOR, E Silva LO, Consentini CEC, Santos OP, Narváez AAC, da Cunha LD et al.

Reproductive outcomes were evaluated in prepubertal Nelore (Bos indicus) heifers submitted or not to two ovulation induction treatment regimens based on progesterone (P4) and estradiol treatments prior to the timed-artificial insemination (TAI). A total of 583 heifers (11.3 ± 1.3&#...