Skip to content
Dosage GuideResearch Reference

MGF Dosage

Research-based dosing protocols, timing guidance, and reconstitution reference for MGF. All information is for educational purposes only.

Quick Answer

MGF (Mechano Growth Factor) dosing remains experimental. Animal studies use 50–200 mcg/kg intramuscularly. Human research typically involves 200-600 mcg injected locally into the targeted muscle group post-workout. PEG-MGF has a longer half-life, allowing for less frequent dosing.

Standard Dosage Range

Research dosing range: 200–600 mcg (MGF), less frequent dosing (PEG-MGF)

Educational reference only

These dosage ranges are derived from preclinical research and community protocols. No human clinical dose-ranging trials have established therapeutic doses for most research peptides. Always consult a qualified healthcare provider before starting any peptide protocol.

Dosage by Use Case

Localized Muscle Growth (MGF)

200–600 mcg1–2× weekly
Duration

4–8 weeks

Intramuscular injection into the targeted muscle immediately post-workout. Cycle with breaks to assess response and minimize potential side effects.

Muscle Recovery (MGF)

200–400 mcg1× weekly
Duration

4–6 weeks

Intramuscular injection post-workout. Lower doses may be sufficient for recovery purposes compared to targeted growth.

Localized Muscle Growth (PEG-MGF)

200-400 mcg1× weekly
Duration

4-8 weeks

PEG-MGF is pegylated which can increase its stability. Requires less frequent dosing compared to standard MGF. Intramuscular injection preferred

Timing & Frequency

Administer MGF immediately post-workout directly into the targeted muscle group. PEG-MGF can be administered at any time but is also preferrably given post-workout.

Cycle Guidance

Given the lack of extensive human data, cycling is recommended. A common approach is 6–8 weeks on, followed by 4–6 weeks off. Monitor for any adverse effects.

Reconstitution Reference

Quick reference for reconstituting MGF. For custom vial sizes and concentrations, use the Reconstitution Calculator.

Common Vial SizeTypically 1–2 mg per vial
BAC Water Volume1 mL bacteriostatic water for 1–2 mg/mL concentration
Concentration & DrawAt 1 mg/mL: 100 mcg = 0.1 mL (10 units on a 100-unit insulin syringe)
StorageRefrigerate at 2–8°C after reconstitution. Keep lyophilized powder at room temperature or refrigerated.
StabilityReconstituted solution stable up to 14 days refrigerated. Lyophilized powder stable 12–24 months per manufacturer specifications.
Use the Reconstitution Calculator → for precise injection volumes based on your exact vial size, water volume, and desired dose.

Frequently Asked Questions

What is the best time to inject MGF?
MGF is most effective when injected directly into the targeted muscle group immediately following a workout. This leverages the elevated IGF-1 levels and enhances satellite cell activation.
What is the difference between MGF and PEG-MGF?
MGF has an extremely short half-life (minutes), requiring frequent injections. PEG-MGF is pegylated, extending its half-life to several hours, allowing for less frequent dosing. PEG-MGF potentially has a more systemic rather than localized effect.
Are there any side effects associated with MGF?
Limited human data exists. Potential side effects include injection site pain, flu-like symptoms, and potential for increased muscle growth in unintended areas (though unlikely). Always start with a low dose.

Last updated: 2026-02-19